istc 2nd Expert Workshop

 

 

 

The Increasing Threat of Infectious Diseases

Bergendal, Sollentuna, Sweden, June 11-13, 2001

 

 

 

 

organised by the Swedish Institute for Infectious Disease Control and The Swedish Defence Research Authority on behalf of the Swedish Ministry of Foreign Affairs

 

 

 

 

IN  CONJUNCTION  WITH

 

 

THE WORLD HEALTH ORGANIZATION

 

 

 

 

 

 

 

 

FINAL REPORT

 

 

 

 

 

Prepared by the team:

 

Dr. Tatiana Gremyakova, Ph.D., M.D.,, SPM

gremyakova@istc.ru

Dr. Diana Pobedimskaya, Ph.D., SPM

pobedimskaya@istc.ru

Mrs. Tatiana Nikolenko, SPM

nikolenko@istc.ru

 

Headed by:

Mr Randall Beatty, Deputy Executive Director

 

CONTENT

 

List of Participants ………………………………………………….

 

 

Summary from Working Group

A. Antimicrobial resistance

B. Surveillance

C. Vector-borne diseases

 

 

Workshop Abstracts ………..………………………………………

 

 

Biosketches .…………..………………………………………………

 

 

 

Review of ISTC-Bio projects ……………………………………………….

 

 

 

BIO-Abstracts ……………………………………………………..

 

 

 

 


 

 

Summary of the Workshop Results

 

Tthe main aim now is to promote health through the acquisition of fundamental knowledge on disease pathogenesis, epidemiology, monitoring, diagnosis and prevention. It is necessary to establish a communications network between clinical laboratories, institutes and public health organizations for more rapid and adequate care with rapid diagnosis by molecular analysis.

All these issues were discussed during the Working Groups Discussion. The participants from USA, EU, Former Soviet Union Republics (Russia, Ukrain, Kazakstan, Georgia, Uzbekistan)  and Japan emphasized the importance of these topics. In this regard, the following approaches should be directed to the of greatest concern:

·        Prevent new infections (monitoring, estimation and forecasting of the condition of health of the population);

·        Understand pathogenic mechanisms;

·        Develop highly sensitive, cheap and specific methods of rapid diagnostics;

·        Develop safe, effective and innovative vaccines against the most dangerous pathogens;

·        Develop new, safe and effective methods of prophylaxi and therapy  of infectious diseases;

·        Creation of information systems to coordinate programs, systemize    information, exchange information on scientific research.

 

 

All the detailed results and working materials of the Workshop are enclosed below.


 

List of Participants

 

Dr. Alim Aikimbayev

Deputy Director in Science and Epidemiological Work

14, Kapalskaya St

Almaty

480074, Kazakhstan

Tel: (3272) 356624, 358829

Fax: (3272) 367641

Email: micro@netmail.kz

 

Yoshichika Arakawa

Director, MD.

National Institute of Infectious Diseases

4-7-1 Gakuen

208-0011 Musashi-Murayama

Tokyo

Japan

Phone: +81 42 561 0771

Fax: +81 42 561 7173

Email: yarakawa@nih.go.jp

 

Dr. Albert Askarov

Kazakhstan, Agency of Health Care

Tel: 7 (3172) 317477

Fax: 7 (3172) 317456

Email: zdrav@kaznet.kz

 

Vladimir Astakhov

Interpreter

Tel: 7 (095) 321-42-61

Fax: 7 (095) 797-60-14

Email: tutukina@istc.ru

 

Dr. Bakyt Atshabar

Director, Kazakh Institute for Research on Plague Control

14, Kapalskaya St

Almaty

480074, Kazakhstan

Tel: 7 (3272) 35-75-58/88-29

Fax: 7 (3272) 36-76-41

Email: kirpc@netmail.kz

 

Dr. Serguei Bajan

Head of the Laboratory

State Research Center of Virology and Biotechnology “Vector”

Koltsovo

Novosibirsk region, Russia, 633159

Tel: (383 2) 324747

Fax: (383 2) 328831

Email: bazhan@vector.nsk.ru

 

Randall Lee Beatty

Deputy Executive Director, ISTC

Tel: 7 (095) 321-42-61

Fax: 7 (095) 797-60-14

Email: beatty@istc.ru

 

Ruth Berkelman

Professor, Department of Epidemiology

Rollins School of Public Health

Room 440

Emory University

1518 Clifton Road

Atlanta, GA 30322

Tel: 404-727-2135

Fax: 404-727-8737

Email: rberkel@sph.emory.edu

 

 

Ivan Bezkopylny

Director, Lviv State Research Institute of Epidemiology and Hygiene

Zelena Str. 12

Lviv 79005 Ukraine

Tel: (380 322) 72-90-69

Fax: (380 322) 76 30 67

 

Olga Borisova

U.S. Embassy

Moscow

Russia

Email: borisovo@state.gov

 

 

Dr. Göran Bucht

Swedish Defence Research Agency (FOI)

SE-901 82  UMEÅ

Sweden

Phone: +46 90 10 66 00
Fax: +46 90 10 68 00

Email: goran.bucht@foi.se

 

Dr. Diego Buriot

Director of WHO/CSR office

Lyon

France

Phone: +33 4 727 6470

Email: buriotd@Lyon.who.int

 

 

Professor Elisabeth Carniel

Director of the National Reference

Centre and WHO Collaborating

Centre for Yersinia

Institut Pasteur

25-28, Rue du Docteur Roux

F-75724 PARIS

France

 

Mr. Dennis Curry

U.S. Embassy

Moscow

Russia

Email: curryde@state.gov

 

Sergei Elovsky

Interpreter

Tel: 7 (095) 321-42-61

Fax: 7 (095) 797060-14

Email: tutukina@istc.ru

 

Dr. Åke Forsberg

Swedish Defence Research Agency (FOI)

SE-901 82  UMEÅ

Sweden

Phone: +46 90 10 66 00
Fax: +46 90 10 68 00

Email: ake.forsberg@foi.se

Sweden

 

Mr. Rob Garverick

American Embassy Moscow

Office of Environment, Science and Technology

Email: garvericjr@state.gov

 

Professor Johan Giesecke

Swedish Institute for Infectious Disease Control

SE-171 82 Solna

Sweden

Phone: +46 8 457 23 00

 

Dr. Yuri Golenyaev

Deputy Executive Director of Biopreparat Company

Russia

Tel: 8 (095) 362 26 56

Fax: 8 (095) 362 15 26

 

Tatiana Gremyakova

Senior Workshop Manager

Tel: 7 (095) 797-60-74

Fax: 7 (095) 797-60-14

Email: gremyakova@istc.ru

 

Elena Gryaznova

Senior Interpreter

Tel: 7 (095) 321-36-11

Fax: 7 (095) 797-60-14

E.mail: gryaznova@istc.ru

 

Peter H. Henry, Ph.D.

Director, Office for Europe and the NIS; OIRH/OPHS/OS

Department of Health and Human Services

Room 18-90 Parklawn Building

5600 Fishers Lane

Rockville, MD 20857

Tel: 301-443-9426

Fax: 301-443-0742

Email: Phenry@osophs.dhhs.gov

 

Dr. Shabat Hodjaev

Director, Institute of Virology

6 opt: 16 Shastri str

Centre 1 700000 Tashkent

Uzbekistan

Tel: (998 712) 24-83-26/24-79-65

 

Dr. Sven Hoffner

Swedish Institute for Infectious Disease Control

SE-171 82 Solna

Sweden

Phone: +46 8 457 24 31

Fax: +46 8 30 1797

Email: sven.hoffner@smi.ki.se

 

Dr. Randy Hyer

WHO Headquarters

20 , Avenue Appia

CH-1211 GENEVA

Switzerland

Phone: +41 22 791 1304
Fax: +41 22 791 4893
Email: hyerr@who.ch

 

Dr. Gulnara Ibadova

Director, Institute of Epidemiology, Microbiology, and Infectious Diseases

700133

Tashkent sh.

Reshetov ko’chasi, 2

Uzbekistan

Tel: (998 712) 43-36-05

Email: reflab@phisic.uzsci.net

Email: rostok.med@online.ru

 

Dr. Paata Imnadze

Director, National Center of Disease Control

Tbilisi, Georgia

Tel:

Fax: 8 (99532)94 04 85

Email: ncdc@access.sanet.ge

 

Dr. Ingegerd Kallings

Swedish Institute for Infectious Disease Control

SE-171 82 Solna

Sweden

Phone: +46 8 457 24 20

 

Jessica Kaplan

Program Specialist

U.S. Civilian Research and Development Foundation (CRDF)

1800 North Kent St., Suite 1106

Arlington, VA  22209

Tel: 703-526-9720, extension 253

Fax: 703-526-9721

Email: jkaplan@crdf.org

 

 

Ms. Maiken Karlsson

Senior Administrative Officer

Swedish Defence Research Agency (FOI)

SE-901 82  UMEÅ

Sweden

Phone: +46 90 10 66 00
Fax: +46 90 10 68 00

Email: maiken.karlsson@foi.se

Sweden

 

Prof. Zura Kesheleva

Science and Epidemiological Work

14, Kapalskaya St

Al-Farati st. 2,79

Almaty

480074, Kazakhstan

Tel: (3272) 356624, 358829

 

Prof. Vsevolod Kiselev

Deputy Director, Center for Molecular Diagnostics and Therapy

Simpheropolsky Blvd 8

Moscow

113 149 Russia

Tel: 7 (095) 113-2365

Fax: 7 (095) 113-2633

Email: svesh@aha.ru

 

Dr. Nikolai Klimov

Deputy Director

Research Institute of UltraPure Biopreparations

Pudozhskaya St, 7

St. Petersburg, Russia, 197110

Tel/fax: (812) 230-48-72

Fax: (812) 2304948

Email: nklimov@mail.ru

 

Alexandr Kosyak

Senior International Health Officer

Department of Health and Human Services

Room 18-90 Parklawn Building

5600 Fishers Lane

Rockville, MD 20857

Tel: 301-443-9426

Fax: 301-443-0742

Email: Akosyak@osophs.dhhs.gov

 

Dr. Birgitta Olsson Lesko

Swedish Institute for Infectious Disease Control

SE-171 82 Solna

Sweden

Phone: +46 8 457 23 00

 

Dr. Pille Lindkvist

Swedish Institute for Infectious Disease Control

SE-171 82 Solna

Sweden

Phone: +46 8 457 23 93

 

Dr. Victor Maleyev

Deputy Director, Central Research Institute for Epidemiology

Tel: 3055270, h 7024435

Fax: 3042209

Email: maleyev@co.ru

 

Dr. Vladimir M. Mikhailovitch

Engelhardt Institute of Molecular Biology

Tel: 315 0559/135 9800

Fax: 1351405

Email lnovikova@genome.eimb.relarn.ru vmikh@aport.ru

 

David Morens

National Institutes of Health

Room 3149

6700-B Rockledge Drive

Bethesda, MD 20892-7630

Tel: 301-496-7453

Fax: 301-480-1594

Email: DM270q@nih.gov

 

Ms. Natalia Mykhaylovska

Project Coordinator

Science and Technology Center in Ukraine

Tel.: +380 (44) 490-7150

Fax: +380 (44) 490-7145

E-mail: nataly@stcu.kiev.ua

 

 

Dr. Kensuke Nakajima

Ministry of Helath, Labour and Welfare

Deputy director, Infection Disease Control Division

1-2-2, Kasumigaseki, Chiyoda-ku

100-8045 Tokyo

Japan

Phone: +81 3 3595 2263

Fax: +81 3 3581 6251

Email: makajima-kensuke@mhlw.go.jp

 

Dr. Aminjon Nematov

Director, Center for Prophylaxis and Quarantine of Most Hazardous Infection

2, E. Bobokhon Street

700169, Tashkent

Uzbekistan

Tel: (998 712) 46-06-05

Fax: (998 712) 46-48-33

 

Dr. Sergei Netesov

Director of the Institute of Molecular Biology

State Research Center of Virology and Biotechnology “Vector”

Koltsovo,

Novosibirsk region, Russia, 633159

Tel: (383 2) 324747

Fax: (383 2) 328831

Email: netesov@vector.nsk.su

 

Tatiana Nikolenko

Senior Project Manager

Tel: 7 (095) 321-47-01

Fax: 7 (095) 797-60-14

Email: nikolenko@istc.ru

 

Daniel Nord

Ministry of Foreign Affairs

SE-103 39 Stockholm

Sweden

Phone: +46 405 10 00

Fax: +46 8 723 11 76

 

Professor Ragnar Norrby

Director-General

Swedish Institute for Infectious Disease Control

SE-171 82 Solna

Sweden

Phone: +46 8 457 2300

 

Barbro Olsson-Liljeqvist

Swedish Institute for Infectious Disease Control

SE-171 82 Solna

Sweden

Phone: +46 8 457 24 68

 

Julie Pavlin

Walter Reed Army Institute of Research

Division of Preventive Medicine

503 Robert Grant Ave.

Silver Spring, MD  20910-7500

Tel: 301-319-9346

Fax: 301-319-9104

Email: julie.pavlin@amedd.army.mil

 

 

Dr. Kenneth Penman
Proliferation Arms Controls Secretariat, UK MOD.

DERA Porton Down,

Salisbury, SP4 OJQ

Wiltshire

UK

Phone: +44 1980 613690

Fax: +44 1980 613311

Email: kjpenman@dera.gov.uk

 

Dr. Mark Perkins

WHO

Avenue Appia 20

Geneva 27

CH-1211

Switzerland

Phone: +41 22 791 4141

Fax: +41 22 791 4854

Email: Perkinsm@who.int

 

Dr. Michel Pletschette

DG KRO/SON 1/122

European Commission

200, rue de la Leri

Bruxelles

Belgium

Phone: +39 2 2956282

Fax: +39 2 296 6252

Email: michel.pletschette.ecec.eu.int

 

 

Ms. Diana Pobedimskaya

Senior Project Manager

Moscow

Russia

Tel: 7 (095) 797-47-61

Fax: 7 (095) 797-60-14

Email: pobedimskaya@istc.ru

 

Dr. Andrei Pokrovsky

Head of the Laboratory of Retroviruses

State Research Center of Virology and Biotechnology “Vector”

Koltsovo,

Novosibirsk region, Russia, 633159

Tel: (383 2) 366011

Fax: (383 2) 328831

Email: pokrovsky@vector.nsk.su

 

Roger Roffey

Director of Research

Swedish Ministry of Defence

Unit for International and Security Affairs

SE-103 33 Stockholm

Sweden

Phone: +46 8 405 4208

Fax: +46 8 10 26 86

Email: roger.roffey@defence-ministry.se

 

 

Elizabeth Scharl

Foreign Affairs Officer

NP/PTR Room 1480

U.S. Department of State

Washington, D.C. 20520

Tel: 202-736-4747

Fax: 202-736-7698

Email: scharlec@T.state.gov

 

 

Dr. Igor Shemyakin

Executive Deputy Director, State Research Center for Applied Microbiology

Obolensk, Serpukhov District

Moscow region, Russia, 142279

Tel: (0967) 360060

Fax: (0967) 360010

Email: info@nrciam.serpukhov.su

 

Thomas Shinnick

Chief of the TB and Mycobacteriology Branch

Mailstop G35

Centers for Disease Control and Prevention

1600 Clifton Road, NE

Atlanta, Georgia 30333

Tel: 404-639-1474

Fax: 404-639-1287

Email: tms1@cdc.gov

 

 

Professor Anders Sjöstedt

Department of Clinical Bacteriology

Umeå university

SE-901 85 Umeå

Sweden

 

Dr. Konstantin Soloviev

Head of Division for Aerosol Toxicometry

Research Center for Toxicology and Hygienic Regulation of Biopreparations

Tel: 7 (0967) 75 97 38

Fax: 7 (0967) 75 97 38

Email: toxic@online.stack.net

 

Thomas Lund Sörensen

International Technical Adviser

Dep. of  Microbiological Research and Development

Statens Seruminstitut

Artillerivej 5

DK-2300 Copenhagen S

Denmark

Phone: +45 32 68 3191

Fax: +45 32 68 3787

Email: tls@ssi.dk

 

 

Professor. Nils Christian Stenseth

Department of Zoology,

University of Oslo,

Oslo, Norway.

Phone: +47 22 85 45 84

Fax: +47 22 8546 05

Email: n.c.stenseth@bio.uio.no

 

 

Nahoko Shindo

Senior Researcher

National Institute of Infectious Diseases

Toyama 1-23-1

Shinjuku-ku

162-8640 Tokyo

Japan

Phone: +81 3 5285 1111

Fax: +81 3 5285 1129

Email: nshindo@nih.go.jp

 

Irina Tutukina

Administrative Assistant

Tel: 7 (095) 321-42-61

Fax: 7 (095) 797-60-14

Email: tutukina@istc.ru

 

Dr. Yukinori Uchida

Director General

Kobe Quarantine Station

Toyahama-eho Hyego-ku

652-0866 Kobe

Japan

Phone: +81 78 672 9651

Fax: +81 78 672 9660

Email: y-uchida@forth.ga.jp

 

Dr. Vladimir Volkov

Deputy Director, State Research Center for Applied Microbiology

Obolensk, Serpukhov district

Moscow region

Russia 142279

Tel: (0967) 36010/36003

Fax: (0967) 360010

Email: volkov@gncpm.serpukhov.su

 

Dr. Ivan Vynograd

Chief of Transmissible Viral Infections Laboratory

Lviv State Research Institute of Epidemiology and Hygiene

Zelena Str. 12

Lviv 79005 Ukraine

Tel: (380 322) 76 31 43

Fax: (380 322) 76 30 67

 

Andrew Weber

Special Advisor for Threat Reduction Policy

The Pentagon, Room 3C288

Washington, D.C. 20301-2900

Tel: 703-693-0289

Fax: 703-614-4365

Email: andyweber@aol.com

 

 


 

 

 

A.  Work Group on Antimicrobial Resistance

 

 

Participants:

 

Yoshichika Arakawa, National Institute of Infectious Diseases, Japan

yarakawa@nih.go.jp

Alim Aikimbayev, Kazakh Institute for Research on Plague Control

micro@netmail.kz

Vsevolod Kiselev, Research Center for Molecular Diagnostics & Therapy, Russia

e.severin@mtu-net.ru

Thomas Shinnick, CDC, USA

tms1@cdc.gov

Kenneth Penman, MOD,UK

kjpenman@dera.gov.uk

Vladimir Mikhailovich, Engelhardt Institute of Molecular Biology, Russia

vmikh@aport.ru

Sven Hoffner, Swedish Institute for Infectious Disease Control, Sweden

sven.hoffner@smi.ki.se

Andrei Pokrovsky,Vector, Russia

pokrovsky@vector.nsc.ru

Thomas Lund Sørensen, SSI (WHO-representative), Denmark

tls@ssi.dk

Igor Shemyakin, GosNIIPM (Applied Microbiology), Russia

shemyakin@nrciam.serpukhov.su

Ingegerd Kallings, Institute of Infectious Disease Control, Sweden

ingegerd.kallings@smi.ki.se

Barbro Olsson-Liljequist, Institute of Infectious Disease Control, Sweden

barbro.olsson-liljequist@smi.ki.se

Diana Pobedimskaya, ISTC, Russia

pobedimskaya@istc.ru

Paata Imnadze, Natinal Center for Disease Control, Georgia

nede@access.sanet.ge

 

 


 

 

Projects in the area of antimicrobial resistance should contain considerations of the following:

 

·         Collaboration between several institutions is encouraged. In particular, collaboration between research institutions and clinical microbiology laboratories. The partners should preferably be institutions abroad as well as institutions in the same country.

·         Projects of surveillance of antimicrobial resistance should be initiated in collaboration between relevant professional groups e.g. clinical microbiologists, hospital infection control committees and hospital pharmacists.

·         In joint projects scientists and clinical institutions may be under guidance of a coordinating body/institution.

·         Training in drug resistance surveillance and site-visits

·         Transfer of knowledge from research in new technologies e.g. molecular techniques to the clinical setting in order to increase the benefit for the patient of the treatment using the advantage of rapid diagnostic results.

·         Secure the application of the outcome of research in the field of molecular science considering the public health perspective, when appropriate.

·         Acknowledge the need for base-line data on resistance frequencies and the use of antimicrobial agents in the community as well as in hospitals

·         The presence of national and local guidelines for e.g. standard operational laboratory  procedures (SOPs), treatment guidelines, national essential drug lists, etc.

·         To participate and/or initiate networks on regional, national and international levels

 

Recommendations

 

Drug resistant tuberculosis

 

1.     Establishment of networks of laboratories to evaluate, standardise and quality assure kits for rapid diagnosis of tuberculosis and drug resistant tuberculosis. 

2.     Use of molecular technologies to study the natural history of drug resistance in TB including spread in “hot spots” e.g. hospitals and prisons and the occupational-risk in health care workers

3.     Availability of anti-TB drugs, the quality of anti-TB drugs and adherence to treatment schemes and the impact of results from these studies on the emergence of resistance in mycobacterium tuberculosis

4.                    Research to identify new targets for anti-TB drugs

 

 

Hospital infections

 

1.        Use of molecular technologies to study the clonal spread of hospital infections

2.        Surveillance using molecular techniques for resistance in hospital acquired infections, including the changing of the treatment schemes and infection control measures

3.        Secure continuous medical education of staff at all levels in order to keep them updated in the newest advances as appropriate

4.        Document effect of infection control measures on e.g. resistance frequencies, number of cases reported, morbidity and containment of outbreaks

 

HIV

 

1.     Use of molecular technologies to study the frequency of resistance in first time diagnosed (untreated infections) cases preferably as part of a surveillance system

2.     Adherence to treatment schemes and development of resistance in HIV

3.     Availability of antiviral drugs and the development of new drugs for treatment of HIV-infection

 


B. WORK GROUP ON PUBLIC HEALTH SURVEILLANCE

 

Scope of the Problem:

 

Participants included representatives from 5 countries, including Russia, Ukraine, Kazakhstan, Georgia, and Uzbekistan.

 

Participants agreed that public health surveillance needs to be improved in all countries.

 

The first priority will be training in two areas.  First, training is needed for epidemiologists that will be part of the modern programs that will be developed.  Second, training is needed for laboratory specialists on new techniques for infectious diseases; training will include scientists who formerly worked in closed facilities.  In addition, some of these scientists from these facilities are likely to be valuable in helping to train other scientists in sophisticated laboratory techniques needed to support public health surveillance. The priority is for in-country training; however, for some specific problems, this training may need to be supplemented by specialized training outside the country.  

 

In particular, training will be focused on high priority diseases, including MDR-tuberculosis,  HIV, sexually transmitted diseases, hepatitis, and emerging infectious diseases.

 

Training of individuals from multiple countries together may be possible and should be considered as training programs are developed.

 

Participants also agreed that information sharing amongst the countries in the CIS is very important. Although hard copies may go from one country to another, it is not clear that those who need to know the information have access to these hard copies.  A website to which all countries in the region could participate was considered an important opportunity.

 

Countries and organizations outside the NIS which are assisting the NIS in improving their communicable disease programs should work to harmonize those programs to the extent possible and in accordance with national policy.

 

 

C. WORK GROUP ON VECTOR-BORN DISEASES

 

Co-Chairs:      Elizabeth Carniel, Pasteur Institute, France

                       Bakyt Atshabar, Kazakh Institute for Research on Plague Control

 

Rapporteurs:    Anders Sjostedt, FOA, Sweden,

                        Aminjan Nematov, Institute of Virology, Uzbekistan

Participants:

 

Åke Forsberg, FOA, Sweden

Elena Gryaznova, ISTC, Russia

Tatiana Gremyakova, ISTC, Russia

Shabat  Hodzaev, Uzbekistan

Paata Imnadze, Georgian CDC

Kensuke Nakajima, Ministry of health, Labour and Welfare, Japan

Aminjon Nematov, Institute of Virology, Uzbekistan

Ivan Vinograd, Lviv State Research Institute of Epidemiology and Hygiene, Ukraine

Andrei Pokrovsky, Vector, Russia

Anders Sjöstedt, FOA, Sweden

Yukinori Uchida, Kobe Quarantine Station, Japan

Andy Weber, DOD, USA

 

 

 

List of Prioritized Regional Infections

 

Almost all the represented countries have natural foci of bacterial, viral and parasite diseases. Among emerging and top prioritised infections 4 were identified -  Congo-Crimean Hemorrhagic Fever, West Nile, borreliosis, plague.

 

In viral infections most acute  are - Congo-Crimean Hemorrhagic Fever, Tick-Borne Encephalites, West Nile, infections caused by group of Arbo- and Hanta-viruses, in bacterial  - Anthrax, Rickettsia, Plague, Borreliosis, Tularemia, Brucellosis, in parasite - Malaria, Leishmania.

 

Important subjects with regard to the prioritized infections

Scientific match-making – usefulness of the workshops - to initiate multi-national collaborations. Important not only to conduct large workshops, but to be able for specialists in one infection to meet  and discuss items for collaboration. As # 1 direction for collaboration surveillance is determined, necessity of development of diagnostics – basic, new, express

Actual for clinical personnel - training -and laboratory-based diagnosis, traditional methods of diagnostics  prioritized for diagnostics of extremely dangerous infections. Prospective is creation of  national training centers.

 

Proposed projects

Actual for :Uzbekistan, Kazakhstan, Ukraine, Georgia, Russia, Kirgisia – CCHF, West Nile, borreliosis – surveillance, epidemiology, therapy

Important for  Uzbekistan, Kazakhstan, Georgia, Russia, Kirgisia - plague, surveillance, epidemiology, therapy

 

The special issue for collaboration  is development of vaccines, e.g., tularemia vaccine as prospective collaborative project  between  Kazakhstan, Russia.

Surveillance and communication in  the area of Aral Sea is of special importance for  Kazakstan and Uzbekistan.

 

Consensus on priorities - National Control System

 

Training (International and regional training centers)

 Epidemiological, laboratory, new staff

Communication - electronic, Internet-access, databases

Diagnostic methods - improve existing, develop new ones